Basic SIBO Protocol: A protocol for naturally treating SIBO effectively.
- Miranda Jones, FMP

- 2 days ago
- 4 min read

Small Intestinal Bacterial Overgrowth (SIBO) affects thousands of people worldwide, causing uncomfortable symptoms like bloating, gas, diarrhea, and abdominal pain. Many struggle to find lasting relief because SIBO requires a targeted approach that addresses its root causes. This post offers a clear, natural protocol to support your body’s healing process and restore gut balance effectively.
What Is SIBO and Why It Is Often Missed
If you’re constantly bloated, reacting to foods, dealing with constipation or diarrhea, and feel like nothing is working… there’s a high chance you’re not dealing with “just IBS.”
You may be dealing with SIBO (Small Intestinal Bacterial Overgrowth).
SIBO happens when bacteria that are supposed to stay in your large intestine start growing in your small intestine, where they don’t belong. Most treatments only address the bacteria, and almost none address why it happened. That’s why so many people go through rounds of antibiotics, diets, and supplements… and it keeps coming back.
Common Signs You May Have SIBO
SIBO doesn’t always show up the same way, but these are the most common patterns I see in patients:
Bloating (especially after eating...even “healthy” foods)
Gas and abdominal pressure
Constipation, diarrhea, or alternating both
Food sensitivities that keep increasing
Brain fog and fatigue after meals
Nutrient deficiencies (iron, B12, vitamin D)
Feeling full quickly or uncomfortable after eating small amounts
If you’ve been told “your labs are normal” but you feel like this daily, something deeper is being missed.
What Actually Causes SIBO: The Root Issues Most People Miss
SIBO develops when your gut environment breaks down.
There are three major systems I look at with every patient:
1. Low Stomach Acid & Weak Digestion
Your stomach acid is your first defense against bacteria.
When it’s low:
Bacteria survive when they shouldn’t
Food sits longer and ferments
Gas and bloating increase
This is extremely common in people with:
Thyroid dysfunction (especially Hashimoto’s)
Chronic stress
Long-term use of acid blockers
H. pylori history
2. Slow Gut Motility (This Is HUGE)
Your gut has a built-in “cleansing wave” called the migrating motor complex (MMC).
It sweeps bacteria out between meals. If this slows down it causes bacteria to build up and SIBO develops.This is one of the biggest reasons people relapse.
Common causes:
Eating too frequently (no gaps between meals)
Nervous system dysregulation
Low thyroid function
Blood sugar instability
Post-viral or post-infectious gut damage
3. Structural or Functional Disruptions
Sometimes the issue is physical or mechanical:
Prior abdominal surgery
Adhesions
Gallbladder removal
Ileocecal valve dysfunction
If flow through the gut is disrupted, bacteria accumulate.
How SIBO Affects Your Labs
SIBO doesn’t just affect digestion, it affects your entire body.
Because nutrients aren’t absorbed properly, I commonly see:
Low ferritin (iron stores) fatigue, hair loss
Low B12 brain fog, nervous system symptoms
Low vitamin D immune + hormone issues
Imbalanced folate
If you’re trying to “fix deficiencies” without fixing your gut, you’ll stay stuck.
How to Test for SIBO
The most common test is a breath test using lactulose or glucose.
It measures:
Hydrogen (often diarrhea type)
Methane (often constipation type)
Hydrogen sulfide (less commonly tested, but important)
But testing alone isn’t enough. You also need to ask: Why did this happen in the first place?
That’s where functional labs come in to look at the whole picture:
Full thyroid panel (NOT just TSH and T4)
Iron panel + ferritin
B12 and folate
Gut testing (when needed)
The Functional Medicine SIBO Protocol:
Depending on type of SIBO and how aggressive the approach needs to be the Elemental Diet may or may not be part of the recommended protocol.
Phase 1: Reduce the Bacterial Overgrowth
Herbal Antimicrobials
Oregano oil
Berberine
Neem
Allicin (especially for methane types)
Elemental Diet (Most Aggressive + Most Effective)
This is a short-term liquid nutrition protocol that:
Starves bacteria
Feeds your body
Reduces symptoms quickly
For severe or stubborn cases, this can be a game-changer. Not all cases. of SIBO will require the Elemental Diet. Do not attempt this portion of the protocol unless being monitored by a physician or practitioner.
Phase 2: Reduce Symptoms with Diet
Common approaches:
Low FODMAP
SIBO Bi-Phasic Diet
Specific Carbohydrate Diet
These reduce fermentation and give your gut a break. But if diet is all you do, SIBO will come back.
Phase 3: Rebuild Digestion
If digestion is weak, bacteria will always return.
This is where we support:
Stomach acid
Digestive enzymes
Bile flow
This step is often skipped and it’s a major reason protocols fail.
Phase 4: Restore Motility (Prevents Relapse)
Without proper motility, SIBO WILL come back.
We focus on:
Meal spacing (4–5 hours between meals)
Prokinetic support (natural or targeted)
Nervous system regulation
Phase 5: Fix the Root Cause
This is what makes results stick. We identify and correct:
Thyroid dysfunction
Chronic stress/nervous system imbalance
Hormonal issues
Blood sugar instability
Post-infectious damage
If this step is skipped, you stay in a cycle.
Why Most SIBO Treatments Fail
Because they only do one of these:
Kill bacteria
Change diet
But they ignore:
Motility
Digestion
Root cause
SIBO is more than a gut issue, it’s a system regulation issue.
Our Approach
When I work with clients, we don’t guess. We:
Identify your type of SIBO
Map your root causeBuild a step-by-step protocol
Support your body through each phase
Prevent relapse (this is the most important part)
We can help!
If you’ve been stuck in cycles of:
Bloating
Food reactions
“Trying everything”
Temporary relief with no lasting results
We hope the basic information provided helps to point you in the right direction. If you need help reach out and let us know! We’ll build a plan specific to your body, your labs, and your symptoms, so you can finally move forward.
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